Colegio Argentino de Cardioangiólogos Intervencionistas Revista Argentina de Cardioangiología intervencionista 2250-7531 2313-9307 15 2 2024 06 30 Initial experience with the Myval ballon-expandable valve in Argentina 0051 0057 EN Federico Blanco Department of Hemodynamics and Interventional Cardiology. Hospital Dr. Argerich (GCABA). Buenos Aires, Argentina. ORCID:0000-0002-3671-7359 federicoluisblanco@gmail.com Juan Pablo De Brahi Department of Interventional Cardiology. Sanatorio de la Trinidad Mitre. Buenos Aires, Argentina.ORCID:0000-0002-0539-9028 Pablo Lamelas Department of Hemodynamics and Interventional Cardiology. Fundación Favaloro. Buenos Aires, Argentina. ORCID:0000-0003-2008-3870 Pablo Spaletra Department of Interventional Cardiology. Instituto Cardiovascular de Buenos Aires. Buenos Aires, Argentina. ORCID:0009-0003-2806-1614 Daniela Coria Department of Interventional Cardiology. Sanatorio de la Trinidad Palermo. Buenos Aires, Argentina. ORCID: 0009-0006-0139-7849 Alejandro Álvarez Iorio Chief of Hemodynamics and Interventional Cardiology. Hospital Italiano Regional del Sur. Bahía Blanca, Argentina. ORCID:0009-0005-2174-621X Ignacio Seropian Department of Hemodynamics and Interventional Cardiology. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.ORCID:0000-0002-6823-4001 Miguel Ballarino Department of Hemodynamics and Interventional Cardiology. Hospital Privado Universitario de Córdoba. Córdoba, Argentina. ORCID: 0009-0001-8279-7943 Jorge Baccaro Chief of Hemodynamics and Interventional Cardiology. Instituto de Cardiología de Corrientes “Juana Francisca Cabral”. Corrientes, Argentina. ORCID: 0009-0008-0539-9028 Carla Agatiello Chief of Hemodynamics and Interventional Cardiology. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. ORCID: 0000-0002-4753-2616 Introduction. Transcatheter valve therapy has revolutionized the treatment of structural cardiovascular disease. The variety of devices developed offers operators the opportunity to choose the most appropriate prosthesis for each type of patient. Balloon-expandable valves can be used as percutaneous treatment in all four cardiac valve positions, and the Myval device, in particular, has unique characteristics that could prove to be advantageous.Objective. To describe the experience of the first 300 Myval balloon-expandable valves implanted in Argentina, including hemodynamic and clinical outcomes, geographic distribution, and operator opinions. Materials and methods. A prospective multicenter registry including the first 300 patients who underwent percutaneous valve replacement in our Argentina with the Myval valve. Primary endpoint: procedural success. Secondary endpoints: all-cause mortality, cardiovascular mortality, stroke, moderate or severe paravalvular leak, and new permanent pacemaker implantation during the hospital stay. Additionally, researchers registered operator opinions regarding the device used.Results. Mean age: 78.7±6.3 years. Mean aortic valve area: 0.72±0.38 cm², with a EuroSCORE II of 6.2%±2.3%. Overall, 95% of the cases featured aortic valve implantation, 2.7% were tricuspid valve implantation, 1.3% were pulmonary valve implantation, and 1% mitral valve implantation. Additionally, 52.3% were conventional-size implants and 47.7% were intermediate (21.5, 24.5, 27.5 mm) or extra-large (30.5, 32 mm) size. Procedural success was 98.7%. There were no patients with severe paravalvular leak. The rate of new permanent pacemaker implantation after transcatheter aortic valve implantation (TAVI) was 6.7%. In-hospital mortality was 2.7%. The study included 78 centers in 16 provinces, with very good acceptance by medical operators. Conclusions. The use of the Myval transcatheter valve prosthesis has proven to be safe and versatile, adapting to cases of high technical complexity. The wide availability of sizes reduces the rate of complications and the need for pacemaker and facilitates the expansion of this alternative to almost all valve areas. The geographic distribution of implants and operator opinions demonstrate broad acceptance and a satisfactory experience. cardiac valve, transcatheter valve implantation, balloon-expandable valve, aortic stenosis, intermediate sizes, extra-large sizes, Myval http://www.raci.com.ar/contenido/art.php?recordID=MjcxNg== http://recursos.meducatium.com.ar/contenido/articulos/34700510057_2716/pdf/34700510057.pdf