Colegio Argentino de Cardioangiólogos Intervencionistas Revista Argentina de Cardioangiología intervencionista 2250-7531 2313-9307 4 03 2013 3- 20 SYNTAX mistakes 0151 0154 EN David Antoniucci Hospital Careggi, Florencia, Italia. david.antoniucci@virgilio.it This revision critically examines results from the SYNTAX study that was recently published the final follow up to 5 years. Therein patients with three-vessel coronary disease or left main trunk of coronary artery were randomized to be treated by coronary angioplasty with 1st generation of drug eluting stents versus coronary artery bypass surgery. In this manuscript we describe potential errors of that study such as: methodological mistakes, selection bias of patients, procedure and so as the technique employed to treat them. All these inaccuracies couldexplained the favorable results of bypass in some subgroups of this study.Maybethe number of stents per patients used and the design of them are the two major limitations of this trial making unable to apply it to the practice of angioplasty at the present time. SYNTAX trial, drug eluting stents, coronary artery bypass surgery, coronary artery disease http://www.raci.com.ar/contenido/art.php?recordID=MTg1 http://recursos.meducatium.com.ar/contenido/articulos/2601510154_185/pdf/2601510154.pdf