Colegio Argentino de Cardioangiólogos Intervencionistas Revista Argentina de Cardioangiología intervencionista 2250-7531 2313-9307 6 04 2015 10 01 Results of renal denervation in clinical practice. Differences between the Flex and Spiral radiofrequency catheters 0176 0179 ES Flavio Ribichini Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy. flavio.ribichini@univr.it Alessia Gambaro Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy. Background: renal sympathetic denervation (RSD) is emerging as a new therapeutic option for patients with severe hypertension refractory to medical therapy. However, results regarding the efficacy of RSD are contradictory. Recently, a new radiofrequency tetrapolar catheter (Symplicity Spiral) has been introduced into clinical practice with the potential for better results. We aimed to compare the results obtained with the first radiofrequency catheter (Symplicity Flex) and the new Symplicity Spiral catheter.Methods: from April 2013 to February 2014, 5 patients were treated with the Flex monopolar catheter (group 1) and from February 2015 to October 2015, 11 patients were treated with the new Spiral tetrapolar catheter. Results: none of the 16 patients treated suffered a complication or adverse event related to the procedure. The blood pressure (BP) reduction in the Flex group was 5 mmHg systolic, and 5 mmHg diastolic BP at 3 months follow-up. In the Spiral group, the systolic BP reduction was 29 mmHg and the diastolic BP 4 mmHg. At three months follow-up, the systolic values were significantly lower compared to baseline (p=0.05). Conclusions: the results obtained in our study with the Symplicity Flex catheter closely reproduce those expected according to the results reported in the HTN III trial in terms of both safety and efficacy. The introduction of the new tetrapolar Symplicity Spiral catheter yielded a significant reduction in systolic BP without adverse events at three months. resistant hypertension, sympathetic renal denervation, radiofrequency http://www.raci.com.ar/contenido/art.php?recordID=NjA= http://recursos.meducatium.com.ar/contenido/articulos/1501760179_60/pdf/1501760179.pdf